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Lotsa stuff, basically scientific -- molecular biology, organic chemistry, medicine (neurology), math -- and music

Most recent posts

It behooves drug chemists to know as much as they can about protein allostery, since so many of their drugs attempt to manipulate it. An earlier post discussed dynamic allostery which is essentially change in ligand binding affinity without structural change...
Isn’t it enough that neural nets beat humans at chess, go and checkers, drive cars, recognize faces, find out what plays Shakespeare did and didn’t write? Not at all. Figuring out how they do what they do may allow us to figure out how the brain...
Drug development is very hard because we don’t know all the players inside the cell. A recent paper describes an entirely new class of player — circular DNA derived from an ancient virus. The authoress is Laura Manuelidis, who would have been a...

Most popular posts

It behooves drug chemists to know as much as they can about protein allostery, since so many of their drugs attempt to manipulate it. An earlier post discussed dynamic allostery which is essentially change in ligand binding affinity without structural change...
Isn’t it enough that neural nets beat humans at chess, go and checkers, drive cars, recognize faces, find out what plays Shakespeare did and didn’t write? Not at all. Figuring out how they do what they do may allow us to figure out how the brain...
Drug development is very hard because we don’t know all the players inside the cell. A recent paper describes an entirely new class of player — circular DNA derived from an ancient virus. The authoress is Laura Manuelidis, who would have been a...