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In an excellent publication "Where do recent small molecule clinical development candidates come from?" DOI, the authors give a detailed description on the development of clinical candidates from the initial hit. They also define the changes in physicochemical...
The Molecular Interactions page has been updated to include a section on anion-aryl interactions....
Just announced. Open Targets Platform release - 18.08.In this release there is now data on:21,149 targets10,101 diseases6.5 million pieces of evidence2.9 million associations between targets and diseasesThe Open Targets Platform is a comprehensive and robust...

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Open Source Malaria (OSM) is aimed at finding new medicines for malaria using open source principles, embodied in the 6 Laws of Open Research. At the moment the majority of work involves the synthesis of analogs of compounds identified by big pharma, with the...
In an excellent publication "Where do recent small molecule clinical development candidates come from?" DOI, the authors give a detailed description on the development of clinical candidates from the initial hit. They also define the changes in physicochemical...
The Molecular Interactions page has been updated to include a section on anion-aryl interactions....

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Update 09  July 2017  I am using this page for Google surfacing experiments for antimalarial structures.  Below are the first few records from a Cambridge MedChem Consulting  instantiation as a findability testOSM Number,Internal ID,PubChem...
It's gratifying to see the paper below appear doi/full/10.1021/acscentsci.6b00086.  Not only is yours truly nested amongst the Ss but I also get an honorable mention in MT's backstory blogpostWhile my own past posts tagged "antimarial" and "OSM" also...