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MIT's Bob Langer has another idea: he's looking to change the way that entire courses of treatment are dosed. What if an extended-release formulation, for an oral drug, was really extended release. Days, weeks? Instead of taking pills every morning,......
This is a neat little structure, and it's truly a pain to synthesize (12 steps from myo-inositol). But it now seems to hold the record as the most polar aliphatic compound ever measured, and well it might. David O'Hagan......
You know, I'm not sure I should have cut Atomwise so much slack the other day. I just came across this piece on them, and. . .well, I'll let it speak for itself: Here I am just sitting in this......

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After reading this piece on Chembark, I find that I have to help defend the whole chem-blogging enterprise. The latest Analytical Chemistry has an editorial from Royce Murray, on the subject. Unfortunately, it sounds like something written several years ago.......
As we approach October, Nobel Speculation Season is upon us again. And Ash is right at Curious Wavefunction - making the predictions gets easier every year, because you get to keep the lists you had from before, with maybe a......
I've had an interesting e-mail from a reader who wants to be signed as "Mrs. McGreevy", and it's comprehensive enough that I'm going to reproduce it in full below. As everyone but the editorial board of C&E; News has noticed,......

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R B Woodward and his followers have solved the general problem of organic synthesis. We need to solve the general problem of design and function.Yesterday's post by Derek titled 'The End of Synthesis'  (follow up here) ruffled quite...
Accounts of Chemical Research - located at the "left of your ACS radio dial"- may be as unloved as the random college radio stations one finds there. Yet it somehow seems to be catching fire with the chemistry "It" crowd.Seriously...it's on the left!I'd...
Last night, while I trudged through Alexander Shulgin's seminal work* PiHKAL, I came upon scrudge, a fantastic heretofore-unknown-to-me term for a very common phenomenon:Love this word: "Scrudge." Defined in the #PiHKAL appendix, meaning low-running TLC...