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There's a new paper out today in Nature on a very unusual way to determine the chirality of organic molecules. It uses an exotic effect of microwave spectroscopy, and I will immediately confess that the physics is (as of this......
Put this one in the category of "reactions you probably wouldn't have thought of". There's a new paper in Organic Letters on cleaving a carbon-carbon triple bond, yielding the two halves as their own separate nitriles. It seems to be......
FiercePharma has some good figures to back up my posts the other day on R&D; spending versus marketing. I mentioned how many people, when they argue that drug companies spend more on marketing than they do on research, are taking......

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After reading this piece on Chembark, I find that I have to help defend the whole chem-blogging enterprise. The latest Analytical Chemistry has an editorial from Royce Murray, on the subject. Unfortunately, it sounds like something written several years ago.......
So here's an unpleasant but necessary topic: what do you do if you're getting out of chemistry entirely? The pharma layoffs of the last few years have made this all too real a decision for too many people, and I......
Here's a blog post at The Washington Post in which a parent asks the musical question: "Why Are You Forcing My Son to Take Chemistry?" It's short, but it can be summarized as My son will not be a chemist.......

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Beth Halford and I sat down to have a quick chat about the life of postdocs, based on her really interesting article in this week's C&EN. It was really fun and the edited recording is below:Timepoints:0:00 - 2:00: What's been the background of postdocs?4:30:...
The Protein Kinase Inhibitor Set (PKIS) made available by GSK was recently mentioned on In the Pipeline. In collaboration with GSK, we are making the data being generated on these compounds available via the ChEMBL database. We are also...
This day has been busy (as you might be able to tell), but a few things to talk about:This C&EN article by Beth Halford on the current state of the postdoc and the problem of chemists taking multiple postdocs is definitely worth a read and worth further...