Explore
Home 
Literature 
Links 
Posts 
Molecules 
Blogs 
Zeitgeist 
Markup Help 
News 

Most recent posts

Have you noticed that Sanofi hasn't named a replacement yet for their ousted CEO Chris Viehbacher? It doesn't seem to be for lack of trying. Stories have come out over the last few months about various people who have been......
Time for another "watch those statistics" post. I did one about this time last year, and I could do one every couple of months, to be honest. Here's a good open-access paper from the Royal Society on the problem of......
I like this reaction, highlighted by See Arr Oh here. It comes in and adds an azide group where there used to be just an alkyl CH bond. That's an instant amine group, naturally, via reduction, as well as an......

Most popular posts

After reading this piece on Chembark, I find that I have to help defend the whole chem-blogging enterprise. The latest Analytical Chemistry has an editorial from Royce Murray, on the subject. Unfortunately, it sounds like something written several years ago.......
As we approach October, Nobel Speculation Season is upon us again. And Ash is right at Curious Wavefunction - making the predictions gets easier every year, because you get to keep the lists you had from before, with maybe a......
I've had an interesting e-mail from a reader who wants to be signed as "Mrs. McGreevy", and it's comprehensive enough that I'm going to reproduce it in full below. As everyone but the editorial board of C&E; News has noticed,......

Latest posts linking here

Last night, while I trudged through Alexander Shulgin's seminal work* PiHKAL, I came upon scrudge, a fantastic heretofore-unknown-to-me term for a very common phenomenon:Love this word: "Scrudge." Defined in the #PiHKAL appendix, meaning low-running TLC...
I grew up on a wonderful little island called Jamestown (although technically it is Conanicut island and the town is Jamestown).  It was a great place to grow up, especially because in the summer we lived walking distance to the beach.  One of the...
As has been noted here, frequently, is that in silico design of fragments is very hard, fraught with problems, and often leads to crap.  As was pointed out elsewhere recently, computational tools are getting more powerful, but still don't have chemical...