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To have your blog items show up on this page, use the semantic markup for InChI's and SMILES, using microformats or RDFa. For example, write <span class="chem:smiles">CCCOC<span> instead of just CCCOC, or <span class="chem:inchi">InChI=1/bla<span> instead of InChI=1/bla.

monosodium phosphate
InChI=1S/Na.H3O4P/c;1-5(2,3)4/h;(H3,1,2,3,4)/q+1;/p-1
PubChem: 24204
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Pinnick oxidation of PMY 2-3 to the corresponding carboxylic acid.Experiment start time: 1015 EST 01/09/11Aldehyde PMY 2-3 (100 mg, 0.46 mmol, 1 equiv.), NaH2PO4 (0.44 g, 3.7 mmol, 8 equiv.) and 2,3-dimethyl-2-butene (0.55 mL, 4.6 mmol, 10 equiv.) were dissolved...
tetrahydrofuran
InChI=1S/C4H8O/c1-2-4-5-3-1/h1-4H2
PubChem: 8028
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Pinnick oxidation of PMY 2-3 to the corresponding carboxylic acid.Experiment start time: 1015 EST 01/09/11Aldehyde PMY 2-3 (100 mg, 0.46 mmol, 1 equiv.), NaH2PO4 (0.44 g, 3.7 mmol, 8 equiv.) and 2,3-dimethyl-2-butene (0.55 mL, 4.6 mmol, 10 equiv.) were dissolved...
In a blatant plug for theReagent Guide, each Friday I profile a different reagent that is commonly encountered in Org 1/ Org 2. Version 1.2 just got released last week, with a host of corrections and a new page index.I'd eat you right now... but I'm...
tert-butanol
InChI=1S/C4H10O/c1-4(2,3)5/h5H,1-3H3
PubChem: 6386
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Pinnick oxidation of PMY 2-3 to the corresponding carboxylic acid.Experiment start time: 1015 EST 01/09/11Aldehyde PMY 2-3 (100 mg, 0.46 mmol, 1 equiv.), NaH2PO4 (0.44 g, 3.7 mmol, 8 equiv.) and 2,3-dimethyl-2-butene (0.55 mL, 4.6 mmol, 10 equiv.) were dissolved...
sodium chlorite
InChI=1S/ClHO2.Na/c2-1-3;/h(H,2,3);/q;+1/p-1
PubChem: 24452
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Pinnick oxidation of PMY 2-3 to the corresponding carboxylic acid.Experiment start time: 1015 EST 01/09/11Aldehyde PMY 2-3 (100 mg, 0.46 mmol, 1 equiv.), NaH2PO4 (0.44 g, 3.7 mmol, 8 equiv.) and 2,3-dimethyl-2-butene (0.55 mL, 4.6 mmol, 10 equiv.) were dissolved...
dimethylformamide
InChI=1S/C3H7NO/c1-3(5)4-2/h1-2H3,(H,4,5)
PubChem: 6228
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Posts

A procedure for the synthesis of 1-(4-fluorophenyl)-2,5-dimethyl-1H-pyrrole-3-carbaldehyde by Vilsmeier-Haack formylation of 1-(4-Fluoro-phenyl)-2,5-dimethyl-1H-pyrrole.DMF (5.0 mL) was stirred under a nitrogen atmosphere in an ice-bath. Phosphoryl chloride...
Oxidation of aldehyde to acid using Oxone (Potassium peroxymonosulfate).Reactions start time: 1600 EST 30/08/11PMY 2-3 (100 mg, 0.46 mmol, 1 equiv.) was dissolved in DMF (5 mL, 0.09 M). Oxone (105 mg, 0.69 mmol, 1.5 equiv.) was added. TLC at 60 mins and 16.5...
Formylation of 1-(4-fluorophenyl)-2,5-dimethyl-1H-pyrrole obtained in experiment PMY 1-4 .Experiment start time: 13.20 EST 22/08/11DMF (1.00 mL, 14.4 mmol, 14.4 equiv.) was stirred under a nitrogen atmosphere in an ice-bath. Phosphoryl chloride (0.12 mL, 1.3...
Scale up of PMY 2-2 to 10.5 mmol scale.Experiment start time: 1433 EST 29/08/11DMF (5.0 mL) was stirred under a nitrogen atmosphere in an ice-bath. Phosphoryl chloride (1.18 mL, 12.7 mmol, 1.2 equiv.) was added and the reaction stirred for 35 minutes. Reaction...
potassium peroxymonosulfate
InChI=1S/K.H2O4S/c;1-4-5(2)3/h;1H,(H,2,3)/q+1;/p-1
PubChem: 61462
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Oxidation of aldehyde to acid using Oxone (Potassium peroxymonosulfate).Reactions start time: 1600 EST 30/08/11PMY 2-3 (100 mg, 0.46 mmol, 1 equiv.) was dissolved in DMF (5 mL, 0.09 M). Oxone (105 mg, 0.69 mmol, 1.5 equiv.) was added. TLC at 60 mins and 16.5...
dimethylformamide
InChI=1S/C3H7NO/c1-3(5)4-2/h1-2H3,(H,4,5)
PubChem: 6228
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Posts

A procedure for the synthesis of 1-(4-fluorophenyl)-2,5-dimethyl-1H-pyrrole-3-carbaldehyde by Vilsmeier-Haack formylation of 1-(4-Fluoro-phenyl)-2,5-dimethyl-1H-pyrrole.DMF (5.0 mL) was stirred under a nitrogen atmosphere in an ice-bath. Phosphoryl chloride...
Oxidation of aldehyde to acid using Oxone (Potassium peroxymonosulfate).Reactions start time: 1600 EST 30/08/11PMY 2-3 (100 mg, 0.46 mmol, 1 equiv.) was dissolved in DMF (5 mL, 0.09 M). Oxone (105 mg, 0.69 mmol, 1.5 equiv.) was added. TLC at 60 mins and 16.5...
Formylation of 1-(4-fluorophenyl)-2,5-dimethyl-1H-pyrrole obtained in experiment PMY 1-4 .Experiment start time: 13.20 EST 22/08/11DMF (1.00 mL, 14.4 mmol, 14.4 equiv.) was stirred under a nitrogen atmosphere in an ice-bath. Phosphoryl chloride (0.12 mL, 1.3...
Scale up of PMY 2-2 to 10.5 mmol scale.Experiment start time: 1433 EST 29/08/11DMF (5.0 mL) was stirred under a nitrogen atmosphere in an ice-bath. Phosphoryl chloride (1.18 mL, 12.7 mmol, 1.2 equiv.) was added and the reaction stirred for 35 minutes. Reaction...
phosphoryl chloride
InChI=1S/Cl3OP/c1-5(2,3)4
PubChem: 24813
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A procedure for the synthesis of 1-(4-fluorophenyl)-2,5-dimethyl-1H-pyrrole-3-carbaldehyde by Vilsmeier-Haack formylation of 1-(4-Fluoro-phenyl)-2,5-dimethyl-1H-pyrrole.DMF (5.0 mL) was stirred under a nitrogen atmosphere in an ice-bath. Phosphoryl chloride...
Formylation of 1-(4-fluorophenyl)-2,5-dimethyl-1H-pyrrole obtained in experiment PMY 1-4 .Experiment start time: 13.20 EST 22/08/11DMF (1.00 mL, 14.4 mmol, 14.4 equiv.) was stirred under a nitrogen atmosphere in an ice-bath. Phosphoryl chloride (0.12 mL, 1.3...
Scale up of PMY 2-2 to 10.5 mmol scale.Experiment start time: 1433 EST 29/08/11DMF (5.0 mL) was stirred under a nitrogen atmosphere in an ice-bath. Phosphoryl chloride (1.18 mL, 12.7 mmol, 1.2 equiv.) was added and the reaction stirred for 35 minutes. Reaction...
InChI=1S/C47H73NO17/c1-27-17-15-13-11-9-7-5-6-8-10-12-14-16-18-34(64-46-44(58)41(48)43(57)30(4)63-46)24-38-40(45(59)60)37(54)26-47(61,65-38)25-33(51)22-36(53)35(52)20-19-31(49)21-32(50)23-39(55)62-29(3)28(2)42(27)56

Posts

Summer can be hot, and many people cool down by jumping in nearby lakes and rivers. However, thats also where millions of microbes like to play: as reported by multiple news outlets, the third 2011 US death has now been attributed to what the popular press...
vemurafenib
InChI=1S/C23H18ClF2N3O3S/c1-2-9-33(31,32)29-19-8-7-18(25)20(21(19)26)22(30)17-12-28-23-16(17)10-14(11-27-23)13-3-5-15(24)6-4-13/h3-8,10-12,29H,2,9H2,1H3,(H,27,28)
PubChem: 42611257
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ATC code: L01XE15Wikipedia: Vemurafenib On the August 17th 2011, the FDA approved Vemurafenib (trade name:Zelboraf TM Research code: PLX-4032, RG-7204 and RO-5185426), a BRAF kinase inhibitor for the treatment of patients with unresectable or metastatic...