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To have your blog items show up on this page, use the semantic markup for InChI's and SMILES, using microformats or RDFa. For example, write <span class="chem:smiles">CCCOC<span> instead of just CCCOC, or <span class="chem:inchi">InChI=1/bla<span> instead of InChI=1/bla.

caffeine
InChI=1S/C8H10N4O2/c1-10-4-9-6-5(10)7(13)12(3)8(14)11(6)2/h4H,1-3H3
PubChem: 2519
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The latest GPCR structure, published in Structure, details three ligand complexes, ZM-241385, a xanthine (XAC) and caffeine. In addition to the interpretation of the complex structures, the paper additionally the use of thermostabilisation as a strategy...
glutathione
InChI=1S/C10H17N3O6S/c11-5(10(18)19)1-2-7(14)13-6(4-20)9(17)12-3-8(15)16/h5-6,20H,1-4,11H2,(H,12,17)(H,13,14)(H,15,16)(H,18,19)/t5-,6-/m0/s1
PubChem: 124886
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Trust your gut . . . scientifically speaking. From belly-button bacteria to classification of signature microflora (all the various microbes that populate the intestinal tract), it feels like recent popular culture grows best in a petri dish. Many scientists...
monosodium phosphate
InChI=1S/Na.H3O4P/c;1-5(2,3)4/h;(H3,1,2,3,4)/q+1;/p-1
PubChem: 24204
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Pinnick oxidation of PMY 2-3 to the corresponding carboxylic acid.Experiment start time: 1015 EST 01/09/11Aldehyde PMY 2-3 (100 mg, 0.46 mmol, 1 equiv.), NaH2PO4 (0.44 g, 3.7 mmol, 8 equiv.) and 2,3-dimethyl-2-butene (0.55 mL, 4.6 mmol, 10 equiv.) were dissolved...
tetrahydrofuran
InChI=1S/C4H8O/c1-2-4-5-3-1/h1-4H2
PubChem: 8028
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Pinnick oxidation of PMY 2-3 to the corresponding carboxylic acid.Experiment start time: 1015 EST 01/09/11Aldehyde PMY 2-3 (100 mg, 0.46 mmol, 1 equiv.), NaH2PO4 (0.44 g, 3.7 mmol, 8 equiv.) and 2,3-dimethyl-2-butene (0.55 mL, 4.6 mmol, 10 equiv.) were dissolved...
In a blatant plug for theReagent Guide, each Friday I profile a different reagent that is commonly encountered in Org 1/ Org 2. Version 1.2 just got released last week, with a host of corrections and a new page index.I'd eat you right now... but I'm...
tert-butanol
InChI=1S/C4H10O/c1-4(2,3)5/h5H,1-3H3
PubChem: 6386
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Pinnick oxidation of PMY 2-3 to the corresponding carboxylic acid.Experiment start time: 1015 EST 01/09/11Aldehyde PMY 2-3 (100 mg, 0.46 mmol, 1 equiv.), NaH2PO4 (0.44 g, 3.7 mmol, 8 equiv.) and 2,3-dimethyl-2-butene (0.55 mL, 4.6 mmol, 10 equiv.) were dissolved...
sodium chlorite
InChI=1S/ClHO2.Na/c2-1-3;/h(H,2,3);/q;+1/p-1
PubChem: 24452
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Pinnick oxidation of PMY 2-3 to the corresponding carboxylic acid.Experiment start time: 1015 EST 01/09/11Aldehyde PMY 2-3 (100 mg, 0.46 mmol, 1 equiv.), NaH2PO4 (0.44 g, 3.7 mmol, 8 equiv.) and 2,3-dimethyl-2-butene (0.55 mL, 4.6 mmol, 10 equiv.) were dissolved...
dimethylformamide
InChI=1S/C3H7NO/c1-3(5)4-2/h1-2H3,(H,4,5)
PubChem: 6228
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A procedure for the synthesis of 1-(4-fluorophenyl)-2,5-dimethyl-1H-pyrrole-3-carbaldehyde by Vilsmeier-Haack formylation of 1-(4-Fluoro-phenyl)-2,5-dimethyl-1H-pyrrole.DMF (5.0 mL) was stirred under a nitrogen atmosphere in an ice-bath. Phosphoryl chloride...
Oxidation of aldehyde to acid using Oxone (Potassium peroxymonosulfate).Reactions start time: 1600 EST 30/08/11PMY 2-3 (100 mg, 0.46 mmol, 1 equiv.) was dissolved in DMF (5 mL, 0.09 M). Oxone (105 mg, 0.69 mmol, 1.5 equiv.) was added. TLC at 60 mins and 16.5...
Formylation of 1-(4-fluorophenyl)-2,5-dimethyl-1H-pyrrole obtained in experiment PMY 1-4 .Experiment start time: 13.20 EST 22/08/11DMF (1.00 mL, 14.4 mmol, 14.4 equiv.) was stirred under a nitrogen atmosphere in an ice-bath. Phosphoryl chloride (0.12 mL, 1.3...
Scale up of PMY 2-2 to 10.5 mmol scale.Experiment start time: 1433 EST 29/08/11DMF (5.0 mL) was stirred under a nitrogen atmosphere in an ice-bath. Phosphoryl chloride (1.18 mL, 12.7 mmol, 1.2 equiv.) was added and the reaction stirred for 35 minutes. Reaction...
potassium peroxymonosulfate
InChI=1S/K.H2O4S/c;1-4-5(2)3/h;1H,(H,2,3)/q+1;/p-1
PubChem: 61462
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Oxidation of aldehyde to acid using Oxone (Potassium peroxymonosulfate).Reactions start time: 1600 EST 30/08/11PMY 2-3 (100 mg, 0.46 mmol, 1 equiv.) was dissolved in DMF (5 mL, 0.09 M). Oxone (105 mg, 0.69 mmol, 1.5 equiv.) was added. TLC at 60 mins and 16.5...
dimethylformamide
InChI=1S/C3H7NO/c1-3(5)4-2/h1-2H3,(H,4,5)
PubChem: 6228
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Posts

A procedure for the synthesis of 1-(4-fluorophenyl)-2,5-dimethyl-1H-pyrrole-3-carbaldehyde by Vilsmeier-Haack formylation of 1-(4-Fluoro-phenyl)-2,5-dimethyl-1H-pyrrole.DMF (5.0 mL) was stirred under a nitrogen atmosphere in an ice-bath. Phosphoryl chloride...
Oxidation of aldehyde to acid using Oxone (Potassium peroxymonosulfate).Reactions start time: 1600 EST 30/08/11PMY 2-3 (100 mg, 0.46 mmol, 1 equiv.) was dissolved in DMF (5 mL, 0.09 M). Oxone (105 mg, 0.69 mmol, 1.5 equiv.) was added. TLC at 60 mins and 16.5...
Formylation of 1-(4-fluorophenyl)-2,5-dimethyl-1H-pyrrole obtained in experiment PMY 1-4 .Experiment start time: 13.20 EST 22/08/11DMF (1.00 mL, 14.4 mmol, 14.4 equiv.) was stirred under a nitrogen atmosphere in an ice-bath. Phosphoryl chloride (0.12 mL, 1.3...
Scale up of PMY 2-2 to 10.5 mmol scale.Experiment start time: 1433 EST 29/08/11DMF (5.0 mL) was stirred under a nitrogen atmosphere in an ice-bath. Phosphoryl chloride (1.18 mL, 12.7 mmol, 1.2 equiv.) was added and the reaction stirred for 35 minutes. Reaction...
phosphoryl chloride
InChI=1S/Cl3OP/c1-5(2,3)4
PubChem: 24813
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Posts

A procedure for the synthesis of 1-(4-fluorophenyl)-2,5-dimethyl-1H-pyrrole-3-carbaldehyde by Vilsmeier-Haack formylation of 1-(4-Fluoro-phenyl)-2,5-dimethyl-1H-pyrrole.DMF (5.0 mL) was stirred under a nitrogen atmosphere in an ice-bath. Phosphoryl chloride...
Formylation of 1-(4-fluorophenyl)-2,5-dimethyl-1H-pyrrole obtained in experiment PMY 1-4 .Experiment start time: 13.20 EST 22/08/11DMF (1.00 mL, 14.4 mmol, 14.4 equiv.) was stirred under a nitrogen atmosphere in an ice-bath. Phosphoryl chloride (0.12 mL, 1.3...
Scale up of PMY 2-2 to 10.5 mmol scale.Experiment start time: 1433 EST 29/08/11DMF (5.0 mL) was stirred under a nitrogen atmosphere in an ice-bath. Phosphoryl chloride (1.18 mL, 12.7 mmol, 1.2 equiv.) was added and the reaction stirred for 35 minutes. Reaction...