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To have your blog items show up on this page, use the semantic markup for InChI's and SMILES, using microformats or RDFa. For example, write <span class="chem:smiles">CCCOC<span> instead of just CCCOC, or <span class="chem:inchi">InChI=1/bla<span> instead of InChI=1/bla.

InChI=1S/C51H40N6O23S6/c1-25-9-11-29(49(60)54-37-13-15-41(83(69,70)71)35-21-33(81(63,64)65)23-43(45(35)37)85(75,76)77)19-39(25)56-47(58)27-5-3-7-31(17-27)52-51(62)53-32-8-4-6-28(18-32)48(59)57-40-20-30(12-10-26(40)2)50(61)5

Posts

Epigenetics is big.  Wicked big.  How big?  This big.  Papers come from everywhere.  In this paper, an academic group from Minnesota, goes after SIRT2 with fragments.  SIRT2 is a type III HDAC that resides primarily in the cytoplasm...
idelalisib
InChI=1S/C22H18FN7O/c1-2-15(28-20-18-19(25-11-24-18)26-12-27-20)21-29-16-10-6-9-14(23)17(16)22(31)30(21)13-7-4-3-5-8-13/h3-12,15H,2H2,1H3,(H2,24,25,26,27,28)/t15-/m0/s1-N


PubChem: -1
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Posts

ATC Code: L01XX47Wikipedia: IdelalisibChEMBL: CHEMBL2216870On July 23rd the FDA approved Zydelig (idelalisib, GS-1101), as an orally-delivered drug to treat patients with three types of blood cancers. Relapsed chronic lymphocytic leukemia (CLL) Relapsed...
pyrazinamide
InChI=1S/C5H5N3O/c6-5(9)4-3-7-1-2-8-4/h1-3H,(H2,6,9)
PubChem: 1046
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Posts

Practical Fragmentshas tried to publicize the dangers of pan-assay interference compounds, or PAINS. These compounds show up as nuisance hits in lots of assays. So what are we to make of a new paper in Curr. Opin. Microbiol. by Pooja Gopal and Thomas Dick,...
dimethyl fumarate
InChI=1S/C6H8O4/c1-9-5(7)3-4-6(8)10-2/h3-4H,1-2H3/b4-3+
PubChem: -1
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Posts

Practical Fragmentshas tried to publicize the dangers of pan-assay interference compounds, or PAINS. These compounds show up as nuisance hits in lots of assays. So what are we to make of a new paper in Curr. Opin. Microbiol. by Pooja Gopal and Thomas Dick,...
1,4-naphthoquinone
InChI=1S/C10H6O2/c11-9-5-6-10(12)8-4-2-1-3-7(8)9/h1-6H-N


PubChem: 8530
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Posts

Practical Fragmentshas tried to publicize the dangers of pan-assay interference compounds, or PAINS. These compounds show up as nuisance hits in lots of assays. So what are we to make of a new paper in Curr. Opin. Microbiol. by Pooja Gopal and Thomas Dick,...
isoniazid#side effects
InChI=1S/C6H7N3O/c7-9-6(10)5-1-3-8-4-2-5/h1-4H,7H2,(H,9,10)
PubChem: 3767
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Posts

Practical Fragmentshas tried to publicize the dangers of pan-assay interference compounds, or PAINS. These compounds show up as nuisance hits in lots of assays. So what are we to make of a new paper in Curr. Opin. Microbiol. by Pooja Gopal and Thomas Dick,...
ethionamide
InChI=1S/C8H10N2S/c1-2-7-5-6(8(9)11)3-4-10-7/h3-5H,2H2,1H3,(H2,9,11)
PubChem: 2761171
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Posts

Practical Fragmentshas tried to publicize the dangers of pan-assay interference compounds, or PAINS. These compounds show up as nuisance hits in lots of assays. So what are we to make of a new paper in Curr. Opin. Microbiol. by Pooja Gopal and Thomas Dick,...
1,4-benzoquinone
InChI=1S/C6H4O2/c7-5-1-2-6(8)4-3-5/h1-4H
PubChem: -1
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Posts

Practical Fragmentshas tried to publicize the dangers of pan-assay interference compounds, or PAINS. These compounds show up as nuisance hits in lots of assays. So what are we to make of a new paper in Curr. Opin. Microbiol. by Pooja Gopal and Thomas Dick,...
tris
InChI=1S/C4H11NO3/c5-4(1-6,2-7)3-8/h6-8H,1-3,5H2
PubChem: 6503
[CML][RDF]

Posts

Guest post by Heather CassellMysteriously abandoned?iStockI love working in the lab. I’m happiest when I’m pottering about among the bottles and the beakers getting on with my work. Most of my experience has been in multi-group labs of varying sizes;...
ethyl carbamate
InChI=1S/C3H7NO2/c1-2-6-3(4)5/h2H2,1H3,(H2,4,5)
PubChem: 5641
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Posts

For reasons that are beyond me, trademarks in the plastics industry tend to become genericized rather easily. Don Loepp of Plastics News has commented on this on more than one occasion. The public uses nylon to describe any polyamide, plexiglas(s) to describe...