At a bail hearing on Friday for University of California, Davis, chemist David Snyder, more details emerged about the case against him for alleged possession and intent to make destructive devices, reckless disposal of hazardous waste, and possession of firearms...

XplA is a P450-flavodoxin fusion enzyme that mediates the metabolism of the military explosive RDX (1,3,5-trinitro-1,3,5-triazinane) in Rhodococcus rhodochrous 11Y [1]. Bui et al. have conducted a detailed spectroscopic and crystallographic study of this unusual...

Pseudomonas fluorescens is a common nonpathogenic Gram-negative bacteria found in poop, soil, and water that gets its name from the fact that it secretes a fluorescent siderophore (iron-binding compound) called pyoverdin (fluorescein). Cultures of it glow under...

Part of the fun of having a blog is monitoring its traffic, and more traffic equals more fun. I say this because, eventually, someone is going to read this blog and finally create a respectable chemistry journal where all of the correspondence—including...

Tonight, we make soap.Matt over at Sciencegeist is organizing this blog carnival in an effort to reclaim the word chemical from the hands of ignorant people who blindly assume anything with chemicals in it must be evil. This is not a moment too soon. Im not...

ATC code: G04BE (partial)Wikipedia: Avanafil On April 27th, the FDA approved Avanafil (tradename: Stendra; Research Code: TA-1790), a phosphodiesterase 5 (PDE5) inhibitor for the treatment of erectile dysfunction (ED). ED is a sexual dysfunction characterized by...

ATC code: G04BE (partial)Wikipedia: Avanafil On April 27th, the FDA approved Avanafil (tradename: Stendra; Research Code: TA-1790), a phosphodiesterase 5 (PDE5) inhibitor for the treatment of erectile dysfunction (ED). ED is a sexual dysfunction characterized by...

Physics Nobel Laureate, legendary teacher and all-round cool guy Richard Feynman once said: [Theres a] difference between knowing the name of something and knowing something. This is true in a whole range of fields, and weve probably all seen enough students...

Lots happening but, sadly, nothing I can blog about. I need to get some RC1 experiments done before I head off to San Diego for the ACS National Meeting and Research Pageant. I really like this Mettler-Toledo RC1 and the sales and support staff. Pretty helpful...

Rydberg states can be seen as ionized molecules that are circled by a loosely bound electron. Because of their diffuse character, the central molecule appears almost like a point charge to the electron. And the states resemble the excited states of atomic hydrogen...

TrippyIt might sound far out (man), but it seems LSD can treat alcoholdependency according to ameta-analysis of previous clinical trials.Lysergic acid diethylamide (LSD, or (8)-N,N-diethyl-6-methyl-9,10-didehydroergoline-8-carboxamide to give it its systematic...

ATC Code: R03BB05Wikipedia: Aclidinium bromide On July 23th, the FDA approved Aclidinum bromide (Tradename: Tudorza PressairTM; Research Codes: LAS-34273, LAS W-330), a muscarinic acetylcholine M3 receptor antagonist, for the long-term maintenance treatment...

Another GPCR structure! - this time the Rat muscarinic M3 receptor, published in Nature, complexed with the drug tiotropium (CHEMBL1201307). 10 20 30 40 50 4dajA ( 64 ) iwqvvfiafltgflAlvTiigNilVivAFkvnkqLktvnnyFllSLAcAD aaaaaaaaaaaaaaaaaaaaaaaaaaaaaa 333...

(This is a post for the #ChemMovieCarnival. Check out the other entries over at Just Like Cooking!)There’s a lot of inaccurate science in movies, but one of the most prevalent is the Hollywood Acid trope. One drop of Hollywood acid is enough to melt a...

A concerned labmate brought my attention to a chemical abomination on last week’s episode of the increasingly unpopular television show House, M.D.Thanks to a very special friend of mine, we can all enjoy video footage of what Hollywood writers believe...