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ABSTRACT: There is an abundance of information about drugs available on the Web. Data sources range from medicinal chemistry results, over the impact of drugs on gene expression, to the outcomes of drugs in clinical trials. These data are typically not connected together, which reduces the ease with which insights can be gained. Linking Open Drug Data (LODD) is a task force within the World Wide Web Consortium's (W3C) Health Care and Life Sciences Interest Group (HCLS IG). LODD has surveyed publicly available data about drugs, created Linked Data representations of the data sets, and identified interesting scientific and business questions that can be answered once the data sets are connected. The task force provides recommendations for the best practices of exposing data in a Linked Data representation. In this paper, we present past and ongoing work of LODD and discuss the growing importance of Linked Data as a foundation for pharmaceutical R&D data sharing.

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An important part of science is communication. That is why we publish. New insights are useless if they sit on some desk. Instead, reuse counts. This communication is not just about the facts, but also a means to establish research networks. Efficient research...
An important part of science is communication. That is why we publish. New insights are useless if they sit on some desk. Instead, reuse counts. This communication is not just about the facts, but also a means to establish research networks. Efficient research...
Almost three years ago I collaborated with others in the W3C Health Care and Life Sciences interest group. One of the results of that was a paper in the special issue around the semantic web conference at one of the bianual, national ACS meeting (look at this...
Last week, Ola, Sam Adams, Arvid, and I published a paper on the InChI functionality in the Bioclipse, which uses Sam's JNI-InChI and the Chemistry Development Kit underneath. This paper partly describes the earlier work by Sam on JNI-InChI itself and the integration...
About half a year ago I was fed up with the slow progress in Open Data in chemistry. Some initiatives exist and some projects, but there is no clear central point of access, which particularly is a problem for smaller providers. Thus, I set out a project plan...
Half a year ago I submitted this abstract for the #ACSNola meeting last week (and as in the slides, I stress that is a large community effort involving not only academic groups but also many pharma companies):Open PHACTS: meaningful linking of preclinicaldrug...
It is a great pleasure (and honor) to be able to speak at the upcoming Herman Skolnik Award Symposium (where Peter Murray-Rust and Henry Rzepa will be awarded). Unfortunately, I will not be present in person and will give my presentation remotely. I will put...
This week I visited the EBI for a set of meetings, among which a CDK hackathon (results will follow later), a Blue Obelisk (doi:10.1186/1758-2946-3-37) pub meetup, and discussions about bioassays. The latter involved a Open PHACTS (doi:10.1016/j.drudis.2012.05.016)...
Hacking up a quick Bioclipse plugin to spider the Linked Open Drug Data network for useful information. The Bioclipse Scripting Language snippet (JavaScript dialect):ui.open( isbjrn.findInfo( cdk.fromSMILES("CCC"), "/Test/test2.html" ))Posted...
Take a look at our ten most accessed papers for October.Six of the top ten papers cover various forms of openness in science, with topics including open access (see Openness as infrastructure), open bibliography (see Open Bibliography for Science, Technology,...
As part of our Open Biblio project Jim and I were looking for lists of journal references to turn in BibJSON. I thought that I’d take some of our article listing from “Visions of a Semantic Molecular Future” (http://www.jcheminf.com/series/semantic_mol_future...
Take a look at our ten most accessed papers for July.Matthias Samwalds paper on linked open drug data continues to be popular and has now become the most accessed paper published in Journal of Cheminformatics this year.An article by Gang Chen about the synthesis...
Take a look at our ten most accessed papers for June. The most popular article over the last month was Matthias Samwalds preliminary communication on linked open drug data. This was part of a thematic series of papers in Journal of Cheminformatics that was...
Journal of Cheminformatics has just published a new Thematic Series of papers covering Resource Description Framework Technologies in ChemistryThe series, edited by Egon Willighagen and Martin Brndle, is based on research presented during three half-day sessions...